Carl Henderson from Flickr.com, a very popular photo blogging service has released a pdf (not sure exactly when this was actually released) detailing the issues they faced with having a high-traffic website.
There are some interesting points on pdf :
- Classes, libraries, and systems used
- smarty for templating
- PEAR and XML for Email parsing
- perl for controlling
- imagemagick for image processing
- mysql (4.0/innoDb)
- java, for node service
- apache 2 and redhat linux
- unicode support
- UTF-8 pages
- CJKV (Chinese, Japanese, Korean and Vietnamese) support